工 作 简 历 和 工 作 业 绩 |
工作经历 1. 2007.08-2009.08 上海交通大学医学遗传研究所助理研究员三级 2. 2009.09-2013.07 中国科学院广州生物医药与健康研究院干细胞与再生医学研究所 助理研究员二级 3. 2014.04-2014.11美国密西根大学 心脏外科系 志愿者 4. 2014.12-2018.08美国密西根大学 心血管内科系 科研技术员 5. 2018.09-2021.03美国密西根大学 心血管内科系 研究专家助理 发表学术论文 1. Wang, Zhenguo; Zhao, Xiangjie; Zhao, Guizhen; Guo, Yanhong; Lu, Haocheng; Mu, Wenjuan;Zhong, Juan; Garcia-Barrio, Minerva; Zhang, Jifeng; Chen, Y. Eugene*; Chang, Lin* ; PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm, JCI Insight,2023, 8(11): e167041 2. Wang Z, Gao X, Li Q, Zhu H, Zhao X, Garcia-Barrio M, Zhang J, Guo Y, Chen YE, Zeng R, Wu JR, Chang L. Inhibition of a Novel CLK1-THRAP3-PPARγ Axis Improves Insulin Sensitivity. Front Physiol. 2021 Aug 30;12:699578. doi: 10.3389/fphys.2021.699578. PMID: 34526909. 3. Chang L*, Zhao X, Garcia-Barrio M, Zhang J, Eugene Chen Y. MitoNEET in Perivascular Adipose Tissue Prevents Arterial Stiffness in Aging Mice. Cardiovasc Drugs Ther. 2018 Oct; 32(5):531-539. doi: 10.1007/ s10557-018-6809-7. 4. Chang L*, Xiong W, Zhao X, Fan Y, Guo Y, Garcia-Barrio M, Zhang J, Jiang Z, Lin JD, Chen YE*. Bmal1 in Perivascular Adipose Tissue Regulates Resting-Phase Blood Pressure Through Transcriptional Regulation of Angiotensinogen. Circulation. 2018 Jul 3;138(1):67-79. doi: 10.1161 /CIRCULATIONAHA. 117.029972. Epub 2018 Jan 25. 5. Xiong W, Zhao X, Villacorta L, Rom O, Garcia-Barrio MT, Guo Y, Fan Y, Zhu T, Zhang J, Zeng R, Chen YE, Jiang Z*, Chang L*. Brown Adipocyte-Specific PPARγ (Peroxisome Proliferator-Activated Receptor γ) Deletion Impairs Perivascular Adipose Tissue Development and Enhances Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2018 Aug; 38(8):1738-1747. doi: 10.1161/ ATVBAHA. 118.311367. 6. Xiong W, Zhao X, Garcia-Barrio MT, Zhang J, Lin J, Chen YE, Jiang Z*, Chang L*. MitoNEET in Perivascular Adipose Tissue Blunts Atherosclerosis under Mild Cold Condition in Mice. Front Physiol. |